Reference:
Rossi, L. F., Harris, K. D., & Carandini, M. (2020). Spatial connectivity matches
direction selectivity in visual cortex. Nature, 588(7839), 648-652.
https://www.nature.com/articles/s41586-020-2894-4
Technique:
Rabies virus tracing of all presynaptic cells and 2P functional imaging
System:
Visual cortex
Summary:
Offers direct evidence that a visual neuron’s orientation and direction selectivity is
predictable from the receptive field properties of neurons it receives synapses from.
Quote:
“We have revealed a precise spatial patterning of excitatory and inhibitory connections
to L2/3 neurons, which can strengthen orientation tuning and establish direction selectivity.”
BPF Journal Club